Diploma in Pharmacy / Бакалавр (Diploma) в Области Фармацевтического Дела

Course Details

Course Information Package

Course Unit TitleORGANIC CHEMISTRY I
Course Unit CodePHA202
Course Unit Details
Number of ECTS credits allocated6
Learning Outcomes of the course unitBy the end of the course, the students should be able to:
  1. Describe the principles of organic chemistry and explain their involvement in the synthesis of pharmaceutical drugs.
  2. Apply the methods and techniques for the preparation of the main groups of aliphatic compounds.
  3. Draw mechanisms of organic reactions.
  4. Describe the particular properties of compounds belonging to the groups, e.g. sugars, lipids, sulphur- and phosphorus- containing compounds.
  5. Draw consecutive reactions for targeted synthesis of organic compounds.
Mode of DeliveryFace-to-face
PrerequisitesPHA101Co-requisitesNONE
Recommended optional program componentsNONE
Course Contents·  Nomenclature of organic compounds.
·  Structure and bonding in organic compounds.
·  Synthesis, properties, reactivity of alkanes, cycloalkanes, alkenes, alkynes, alkyl halides, alcohols, ethers, epoxides, amines, carbonyl compounds, organometallic compounds, sulphur and phosphorus containing compounds.
·  Stereochemistry. Stereochemistry in organic reactions.
·  Nucleophilic substitution, addition and elimination reactions and the involved mechanisms.
·  Mechanisms of selected organic reactions, some name reactions.
·  Separation of organic compounds using chemical and chromatographic techniques.
·  Sugars and lipids.
Laboratory work: Distillation and crystallisation, Esterification, hydrolysis, saponification, Synthesis of ethers, Quaternisation of a tertiary amine, Carbonyl reactions and identification, Grignard reactions.
Recommended and/or required reading:
Textbooks
  • J. Clayden, N. Greeves, S. Warren and P. Wothers, Organic Chemistry, Oxford University Press, UK, 2000.
References
  • M.B. Smith, J. March, March’s Advanced Organic Chemistry, Wiley Interscience, 2007.
Planned learning activities and teaching methodsThe taught part of course is delivered to the students by means of lectures, conducted with the help of computer presentations. Lecture notes and presentations are available through the web for students to use in combination with the textbooks.
Lectures are accompanied with tutorials and laboratory work which is carried out in the chemistry laboratory.
Assessment methods and criteria
Laboratory20%
Tests20%
Final Exam60%
Language of instructionGreek
Work placement(s)NO

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