Diploma in Pharmacy / Бакалавр (Diploma) в Области Фармацевтического Дела

Course Details

Course Information Package

Course Unit TitleBIOCHEMISTRY I
Course Unit CodePHA207
Course Unit Details
Number of ECTS credits allocated5
Learning Outcomes of the course unitBy the end of the course, the students should be able to:
  1. Identify the importance and contribution of biochemistry in the advancement of medicine and pharmacy.
  2. Identify the biomolecules and explain their chemical composition, biological function and role.
  3. State the properties of biomolecules and distinguish the ways these properties manage to set the body functions.
  4. Analyse the ways our body metabolizes molecules and how these functions are influenced by hormones, vitamins and inorganic compounds.
  5. Explain the biochemical basis of disease.
Mode of DeliveryFace-to-face
PrerequisitesPHA202Co-requisitesNONE
Recommended optional program componentsNONE
Course Contents·  Introduction to biochemistry and background: The contribution of biochemistry to the advancement of medicine and pharmacy. Basic concepts in biochemistry and biology: life, living matter, atoms, molecules, chemical bonds, hydrogen bonds, water, acids, bases, pH, solutions and buffers, solution concentrations, thermodynamics, cell organelles.
·  Proteins: Structure and biological role of amino acids. Peptides and proteins. Primary and 3-dimentional structure of proteins. Protein folding. Proteins function. Study of structure and function of hemoglobin.
·  Sugars and polysaccharides: Monosaccharides, polysaccharides. Structure and function of glucose. Structure and function of glycoproteins.
·  Lipids and membranes: Lipid classification. Fatty acids, phospholipids, triglycerides. Lipid aggregates and biological membranes. Structure of cell membrane. Lipoproteins. Cholesterol structure and role. Steroids.
·  Metabolism: Introduction to metabolism. Glycolysis. Glycogen metabolism. Hormones. Membrane transport. Citric Acid Cycle. Electron transport and oxidative phosphorylation. Plant cells, chlorophyll and photosynthesis (dark and light reactions). Metabolism of lipids. Ketone bodies. Amino acid metabolism and urea cycle. Metabolism of nucleotides.
Laboratory Work: Individual or small group experiments performed using common biological science equipment. Students become acquainted to techniques involving protein isolation, chromatographic separation, electrophoresis, lipid, sugar isolation and study of their properties.
Recommended and/or required reading:
Textbooks
  • J. M . Berg , J. L . Tymoczko , L. Stryer, Biochemistry, Part I and II, 5th Edition, 2002.
References
  • D.L. Nelson, M.M. Cox, Lehninger Principles of Biochemistry, W.H. Freeman & Company, 2008.
Planned learning activities and teaching methodsThe taught part of course is delivered to the students by means of lectures, conducted with the help of computer presentations. Lecture notes and presentations are available through the web for students to use in combination with the textbooks.
Lectures are supplemented with laboratory work carried out in a Biology and Biochemistry laboratory.
Assessment methods and criteria
Tests20%
Laboratory work20%
Final Exam60%
Language of instructionGreek
Work placement(s)NO

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