Diploma in Pharmacy / Бакалавр (Diploma) в Области Фармацевтического Дела
Course Details
Course Information Package
| Course Unit Title | BIOCHEMISTRY II |
| Course Unit Code | PHA304 |
| Course Unit Details | |
| Number of ECTS credits allocated | 5 |
| | Learning Outcomes of the course unit | By the end of the course, the students should be able to:- Identify the biomolecules and explain their chemical composition, biological function and role.
- State the properties of biomolecules and distinguish the ways these properties manage to set the body functions.
- Analyse the structure, function and control of enzymatic activity.
- Analyze the structure, function of genetic material.
- Explain the genetic basis of disease.
|
| Mode of Delivery | Face-to-face |
| Prerequisites | PHA207 | Co-requisites | NONE |
| Recommended optional program components | NONE |
| Course Contents | · Enzymes: Substrate specificity. Coenzymes. Properties of enzymes. Regulation of enzymatic activity. Enzyme inhibition and induction. Allosteric enzymes. Enzyme antagonists. Rates of enzymatic reactions. Enzymatic catalysis. Examples of enzymatic reactions. Vitamins.
· DNA: Nucleotides and nucleic acid structure. Double helix and base pairing. DNA replication, repair and recombination.
· RNA: Nucleotides and RNA structure. mRNA, rRNA, tRNA.
· Transfer of genetic information: Transcription and Translation. ribosomes and the genetic code.
· Genes: The structure of chromosomes. Heredity. Eukaryotic gene expression. DNA mutations.
· Genetic disease: The genetic basis of various diseases and genetic syndromes.
· DNA technology: Cloning and genetic engineering. GMOs.
Laboratory Work: Individual or small group experiments performed using common biological science equipment. Students become acquainted to techniques involving enzymatic reactions, nucleic acid isolation and study. |
| Recommended and/or required reading: |
| Textbooks | - J. M . Berg , J. L . Tymoczko , L. Stryer, Biochemistry, Part I and II, 5th Edition, 2002.
|
| References | - D.L. Nelson, M.M. Cox, Lehninger Principles of Biochemistry, W.H. Freeman & Company, 2008.
|
| Planned learning activities and teaching methods | The taught part of course is delivered to the students by means of lectures, conducted with the help of computer presentations. Lecture notes and presentations are available through the web for students to use in combination with the textbooks.
Lectures are supplemented with laboratory work carried out in a Biology and Biochemistry laboratory. |
| Assessment methods and criteria | | Tests | 20% | | Laboratory | 20% | | Final Exam | 60% |
|
| Language of instruction | Greek |
| Work placement(s) | NO |
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