Diploma in Pharmacy / Бакалавр (Diploma) в Области Фармацевтического Дела

Course Details

Course Information Package

Course Unit TitlePHARMACEUTICAL IMMUNOLOGY & IMMUNOCHEMISTRY
Course Unit CodePHA310
Course Unit DetailsInt.M. Pharmacy (Required Courses) - BSc Pharmacy (Required Courses) -
Number of ECTS credits allocated6
Learning Outcomes of the course unitBy the end of the course, the students should be able to:
  1. Recognise the immune system, its components, function and molecular biology, as well as its chemistry.
  2. State why it fails sometimes.
  3. Distinguish the role of various immune cells, anti-inflammatory and inflammatory agents.
  4. Explain about the production of antibiotics, vaccines, their technology and use.
  5. Analyse the use of antibodies in therapeutics and how to develop drugs targeting certain cells or tissues.
  6. Analyse the use of antibodies in immunotherapy and diagnostics.
Mode of DeliveryFace-to-face
PrerequisitesPHA203,PHA207Co-requisitesNONE
Recommended optional program componentsNONE
Course Contents�  Introduction to immunity-immunology and immunochemistry.
�  Components of the immune system. Function of organs and cells of the immune system. Antibodies and complement antibody preparation. Cellular responses in immunity.
�  Antibodies as drugs and drug carriers. Commercial antibodies used as drugs.
�  Chemo-immunotherapy, Radio-immunotherapy.
�  Hypersensitivity and drug allergy. Humoral and cellular immunodeficiency.
�  Cytokines, e.g. interleukins, interferons, and immunotherapy.
�  Infectious diseases. Vaccines, immune response, duration of immunity, types of vaccines, technology of vaccines. Immunological agents as drugs, antibodies. Immunodiagnostics and immunoassays. Inflammation and role of the non steroidal anti-inflammatory drugs.
�  Chemistry of antigens, immunoglobulins and antibodies. Antibody - antigen interactions, e.g. precipitation, agglutination reactions. Biologic - biochemical activities of antibodies e.g. complement fixation.
�  Autoimmune diseases. Transplantations. Pregnancy, cancer, nutrition and immunity.
�  Laboratory: Production of antibodies in rabbits; Immunoprecipitation in diagnostics; Inflammation and anti-inflammatory action.
Recommended and/or required reading:
Textbooks
  • Λ. Χατζηπέτρου-Κουρουνάκη, Ανοσοβιολογία, University Studio Press, Θεσσαλονίκη, 1995.
References
  • I. Roitt, J. Brostoff, D. Nale, Immunology, Mosby, 6th edition, 2001.
Planned learning activities and teaching methodsThe taught part of course is delivered to the students by means of lectures, conducted with the help of computer presentations. Lecture notes and presentations are available through the web for students to use in combination with the textbooks.
Lectures are supplemented with laboratory work carried out in a Biology and Biochemistry laboratory.
Assessment methods and criteria
Tests20%
Laboratory work20%
Final Exam60%
Language of instructionGreek
Work placement(s)NO

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