Diploma in Pharmacy / Бакалавр (Diploma) в Области Фармацевтического Дела

Course Details

Course Information Package

Course Unit TitlePHARMACOGNOSY
Course Unit CodePHA404
Course Unit Details
Number of ECTS credits allocated6
Learning Outcomes of the course unitBy the end of the course, the students should be able to:
  1. Identify most of the known common pharmaceutical plants and the main chemical components of selected important medicinal plants.
  2. Identify the characteristic phytochemical analytical methods for detecting the main chemical constituents of the medicinal plant parts, e.g. folia cannabis and recognise the basic methods of extracting the main active secondary metabolites from pharmaceutical plants.
  3. State the origin and Phytogeography of several pharmaceutical plants, e.g. Zea mays, America, Scilla maritima, Greece and Cyprus.
  4. Distinguish the analytical methods to control the quality of herbal medicinal products in accordance with the European Pharmacopoeia.
  5. Distinguish the common adulterations of herbal medicinal products and the methods to control them.
  6. Employ the methods for improving the quality of herbal medicinal products based on the conditions of cultivation (Good Cultivation Practice).
  7. Employ basic principles for the safe use of plants.
Mode of DeliveryFace-to-face
PrerequisitesPHA204Co-requisitesNONE
Recommended optional program componentsNONE
Course Contents·  Most important and extensively used in Pharmacy, Pharmaceutical Industry and Perfumery plant products, and their chemical constituents, i.e. primary metabolites such as carbohydrates and derivatives, e.g. glycosides, proteins, lipids, and secondary metabolites, such as terpenoids, steroids, polyphenols (phenolic acids, alcohols, esters, flavonoids, coumarins, antraquinones, tannins), essential oils, alkaloids, pigments, vitamins. Appearance, anatomical, histochemical characteristics of each plant product, distribution in the plant, binomial botanical name of the producing plant and its family. Description of the plant and its phytogeography. Action and use of the plant products and their main active constituents. Control and assays for detecting adulteration, i.e. physical state, appearance, anatomical characteristics and chemical analysis. Emphasis will be given to plants used as crude therapeutic agents for extraction of the active material, or used as such, e.g. for obtaining anticancer, antiviral or antineurodegenerative drugs.
·  Non conventional methods, e.g. plant cell cultures, hairy roots and genetic engineering, for amelioration of medicinal plants. Social, ethical and other questions arising from the human intervention in the plant cell genetic material. Differences between plant and animal cells in this respect. Medicinal and aromatic plants of Cyprus. Research and efforts for adaptation of foreign plants of high economic value, as sources of medicine or aromatic constituents, to the environmental conditions of Cyprus, e.g. climate, temperature, humidity and chemical constitution of the soil.
·  Safe use of herbal medicinal products by the pharmacists and Regulatory Affairs: Directive of EU 2001/83 EC as amended by 2004/24/EC (European Medicines Agency - EMA) and its Committee responsible for Herbals (HMPC- Herbal Medicinal Products Committee)
·  Laboratory: Preparation of an extract from a pharmaceutical plant containing, e.g. alkaloids, anthraquinones sugars and/or flavonoids, saponins; Separation of a mixture and identification of at least three alkaloids; Field work, finding and identification of at least eight medicinal or aromatic plants; Steam distillation or extraction of essential oil from aromatic plants; Chemical, physicochemical and physical characterisation of the obtained essential oils.
Recommended and/or required reading:
Textbooks
  • G. Samuelson and L. Bohlin, Drugs of Natural Origin: A Treatise of Pharmacognosy, Sixth Revised Edition, Swedish Pharmaceutical Press, 2010, and a Greek translation of an older edition, published by The University Press of Crete.
  • C. Souleles, A. Simoni, Pharmacognosy, 2000.
  • J. Bruneton, Pharmacognosy-Phytochemistry Medicinal plants, Eds Intercept Ltd, Paris-NY, 2001.
  • W.C. Evans, Pharmacognosy, Ed Bailliere Tindall, 2007.
References
  • K. Torssell, Natural Product Chemistry: A mechanistic, biosynthetic and ecological approach”, Swedish Pharmaceutical Press, 1997.
  • M. Heinrich, J. Barnes, S. Gibbons, Fundamentals of pharmacognosy and phytotherapy”, E. Williamson Ed. Churchill Livingstone- London, 2006.
  • http://www.ema.eu.ema/index.jsp?curl=/pages/medicines/landing/herbalsearch
Planned learning activities and teaching methodsThe taught part of course is delivered to the students by means of lectures, conducted with the help of computer presentations. Lecture notes and presentations are available through the web for students to use in combination with the textbooks.
Lectures are supplemented with laboratory work carried out in a pharmaceutical analysis laboratory.
Assessment methods and criteria
Tests20%
Laboratory work20%
Final Exam60%
Language of instructionGreek
Work placement(s)NO

 Печать  E-mail