Course Details
Course Information Package
| Course Unit Title | CLINICAL PHARMACY & DRUG INTERACTIONS | ||||||||
| Course Unit Code | PHA406 | ||||||||
| Course Unit Details | |||||||||
| Number of ECTS credits allocated | 6 | ||||||||
| Learning Outcomes of the course unit | By the end of the course, the students should be able to:
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| Mode of Delivery | Face-to-face | ||||||||
| Prerequisites | NONE | Co-requisites | NONE | ||||||
| Recommended optional program components | NONE | ||||||||
| Course Contents | This course prepares, assisted by the rest of the pharmacy curriculum, a prospective pharmacist, especially clinical pharmacist, to assist and collaborate with the medical doctor in the hospital ward, in problems of pharmacotherapy, setting of therapeutic scheme, drug doses, drug interactions and determination of drug and main drug metabolite levels in biological fluids (blood, urine, feces, cerebrospinal fluid, saliva).The following are included: · Principles of pathophysiology of diseases and therapeutics. · Approaches in pharmacotherapy, decision of the appropriate therapeutic scheme, drug doses. · Role of age, sex, race, body weight, diet, pregnancy, lactation, diabetes, renal, liver heart dysfunctions. · Multi drug therapies. · Pharmaceutical, pharmacokinetic (absorption, distribution, metabolism excretion), pharmacodynamic drug-drug and drug-food interactions. · Correlation of structure and physicochemical properties with therapeutic efficacy and safety of drugs. · Chemical analysis, detection and quantitative determination of drugs and drug metabolites in biological fluids. Laboratory Work: Determination of a drug, e.g. aspirin or paracetamol, and the main metabolite in urine (by GLC or HPLC), Determination of a drug, e.g. quinine or caffeine, in blood, Investigation of the simultaneous administration of a dose (0.1 mg) of digitoxin and of a high dose (1.5 g) of aluminium hydroxide, Investigation of the effect of zoxazolamine, a centrally acting muscle relaxant, administered after a 4-day treatment with Phenobarbital, Series of 2h visit to a hospital ward, with a physician, and discussion with the responsible teacher in the presence of the physician. | ||||||||
| Recommended and/or required reading: | |||||||||
| Textbooks |
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| References |
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| Planned learning activities and teaching methods | The taught part of course is delivered to the students by means of lectures, conducted with the help of computer presentations. Lecture notes and presentations are available through the web for students to use in combination with the textbooks. Lectures are supplemented with laboratory work carried out in a pharmaceutical chemistry laboratory. | ||||||||
| Assessment methods and criteria |
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| Language of instruction | Greek | ||||||||
| Work placement(s) | NO | ||||||||
