Course Details
Course Information Package
Course Unit Title | INTRODUCTION TO PHARMACEUTICAL BIOTECHNOLOGY | ||||||||
Course Unit Code | PHA407 | ||||||||
Course Unit Details | |||||||||
Number of ECTS credits allocated | 6 | ||||||||
Learning Outcomes of the course unit | By the end of the course, the students should be able to:
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Mode of Delivery | Face-to-face | ||||||||
Prerequisites | PHA210,PHA304 | Co-requisites | NONE | ||||||
Recommended optional program components | NONE | ||||||||
Course Contents | · Global significance of biotechnology, categories of biotechnology processes and products. · Genomics, proteomics, metabolomics. · Essentials of recombinant DNA technology. Production of recombinant DNA, gene mapping, cloning systems and gene libraries. · Mutation detection techniques. · Protein and enzyme engineering, theory and methods. Production and purification of pharmaceutical proteins and monoclonal antibodies and their applications. Principles of genetic engineering, specific production of agents useful in pharmacy and therapeutics, secondary plant metabolites, vectors of genetic material. · Genetic modifications of organisms used in pharmaceutical sciences. Gene knock-out animal models and transgenic animals. · Genetic diseases and gene therapy. Pharmacogenetics. · Tissue cultures. Cellular assays in drug discovery. Fermentation technology. Bioreactors. From the human genome to new drugs, possible prospects. · Ethical issues. · Laboratory Work: Cell culture, tissue culture, assay of drug action using hepatocyte cultures, plasmid DNA extraction from bacteria, PCR technique, biofermentation – biofermentors | ||||||||
Recommended and/or required reading: | |||||||||
Textbooks |
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References |
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Planned learning activities and teaching methods | The taught part of course is delivered to the students by means of lectures, conducted with the help of computer presentations. Lecture notes and presentations are available through the web for students to use in combination with the textbooks. Lectures are supplemented with laboratory work carried out in the Biology and Biochemistry laboratory. | ||||||||
Assessment methods and criteria |
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Language of instruction | Greek | ||||||||
Work placement(s) | NO |