| Course Unit Title | CELL BIOLOGY AND GENETICS |
| Course Unit Code | NUR112 |
| Course Unit Details | |
| Number of ECTS credits allocated | 5 |
| | Learning Outcomes of the course unit | By the end of the course, the students should be able to:- Describe the basic cell biology principles
- Describe the chemical composition of the cell
- Describe the cytoskeleton and cell movement
- Explain the genetic basis of various diseases and the impact of Genetics in disease diagnosis, prevention and treatment
- Extract conclusions from data
|
| Mode of Delivery | Face-to-face |
| Prerequisites | NONE | Co-requisites | NONE |
| Recommended optional program components | NONE |
| Course Contents | · Introduction to cell structure: Types of cells: Eukaryotic and prokaryotic cells. Comparison of cells. Observation of cells under the microscope.
· Chemical composition of cells: Biological molecules of the cell. Protein structure and function
· Internal cellular organelles
· Energy production in cells: Mitochondria and cell respiration (oxidative phosphorylation). Chloroplasts and photosynthesis
· Cell membrane - Cytoskeleton: Structure and permeability. Membrane proteins. Intracellular transfer. Cell communication
· Cell cycle: Mitosis and meiosis. Cell death
· The genetic code: DNA structure and function. DNA replication and repair. Transcription (DNA to RNA) and translation (RNA to protein). Chromosomes, genes and regulation of gene expression. Genetic diversity. Genetic diseases and chromosomal abnormalities. Cancer and oncogenes
· DNA technology: DNA analysis. Research in biomedical sciences. Gene therapy. Cloning. Genetic mechanisms
- Laboratory: Βacteria. Ε.coli culture. Μicroscopy. Observation of different types of cells under the microscope. DNA extraction from plant tissue. Exercises for understanding of DNA structure and the processes of DNA replication, transcription and translation
|
| Recommended and/or required reading: |
| Textbooks | - K. Charvalou, D. Pigis, D.Κ. Philipou and G. Τringas, Concise Cell Biology, Paschalides Medical Editions, 2002
|
| References | - B. Alberts, D. Bray, K. Hopkin, A. Johnson, J. Lewis, M. Raff, K. Roberts, P. Walter, Basic Principles of Cell Biology, Volumes Ι and ΙΙ, Paschalides Medical Editions, 2006
- J. Berg, J. Tymoczko and L. Stryer, Βiochemistry, Volumes Ι and ΙΙ, Crete Editions, Athens 2005
- Α. Read, Modern Clinical Genetics, Paschalides Medical Editions, Athens 2010
|
| Planned learning activities and teaching methods | The course is delivered to the students by means of lectures, conducted with the help of computer-based presentations. Lecture notes and presentations are available through the web for students to use in combination with the textbooks. The evaluation of the laboratory experiments and exercises was performed with the completion of special questionnaires. Before each laboratory exercise the lecturer was preparing and demonstrating the experiment |
| Assessment methods and criteria | | Participation | 10% | | Tests | 30% | | Laboratory | 10% | | Final Exam | 50% |
|
| Language of instruction | Greek |
| Work placement(s) | NO |
