BSc in Mechanical Engineering

Course Details

Course Information Package

Course Unit TitleBIOMEDICAL ENGINEERING
Course Unit CodeAMEM420
Course Unit Details
Number of ECTS credits allocated5
Learning Outcomes of the course unitBy the end of the course, the students should be able to:
  1. Identify the mechanism by which medical devices and implants come to market.
  2. Understand the interrelation of design and research in bioengineering
  3. Identify, formulate, and solve bioengineering problems.
  4. Explain the requirements for materials used in the body and assess potential for implant-body interactions
  5. Explain the different mechanical properties of biomedical materials.
  6. Explain the mechanical behaviour of joints and muscle forces, mechanical properties of biological tissues
  7. Design and test new implants by selecting various biomedical materials.
  8. Identify appropriate tissue engineering approaches for different tissues and organs.
Mode of DeliveryFace-to-face
PrerequisitesNONECo-requisitesNONE
Recommended optional program componentsNONE
Course Contents Introduction to the main biomedical materials: ceramics, metals and polymers. Their structure, properties and manufacture with regard to the various biomedical applications ranging from implants to devices based on engineered tissues.

Various medical imaging modalities (x-rays, CT, MRI, ultrasound, PET, SPECT, optical imaging, etc.) and their applications in medicine. Extends basic concepts of signal processing to the two and three dimensions relevant to imaging physics, image reconstruction, image processing, and visualization.

Relationships between structure and properties of synthetic implant materials, including metals, polymers, ceramics, and composites. Mechanical, corrosion, and surface properties of materials. Blood-material interactions. Biocompatibility with special emphasis on the interaction of biomaterials with cells and tissues in the context of implant surface design and tissue engineering.

Application of mechanics in modeling the biomechanical behavior of tissues such as tendons, ligaments, skin, cartilage, blood vessels, etc. Structure of collagen, elastin, proteoglycans, and other tissue components, nonlinear elastic models, linear viscoelasticity.

Structure-property relationships for mineralized connective tissues of the human body. Discussion centers on various types of bone (e.g., lamellar, woven) with an emphasis on models for biomechanical behavior. Elastic models for bone (isotropic and anisotropic), theories of yielding and fatigue, strength properties, composite and hierarchical models, and models of bone remodeling/modeling.

Application of mechanics to the study of normal, diseased, and traumatized musculo-skeletal system. Determination of joint and muscle forces, mechanical properties of biological tissues, and structural analysis of bone-implant systems. Role of biomechanics and biomaterials in the design of implants.

Theory and practice of biomedical measurements. Instruments and procedures for measurement of pressure, flow, bioelectrical potentials, cell counting, biomechanical and biomaterial properties, using invasive and noninvasive techniques. Transducers studied include strain gauge, differential transformer, spectrophometer, bipotential electrodes, microscope with camera, mechanical testing machine, piezoelectric transducer (or sensor). Determination of material properties.

Introduction of mathematical and computational methods to model physiological systems in biomedical engineering that include examples drawn from thermal and therapeutic diffusion, biomechanics of the musculoskeletal system, and lumped parameter models of the cardiac cycle. Computational methods using commercial programming and finite element software.

Assignments: Individual assignments
Recommended and/or required reading:
Textbooks
  • Biomaterials: An Introduction. By J. Park and R. Lakes, Springer, 2007
  • Biomaterials, artificial organs and tissue engineering, by L Hench, J Jones. Woodhead Publishing, 2005.
  • Basic Orthopaedic Biomechanics and Mechanobiology, third edition, Mow VC and Huiskes R. Philadelphia: Lippincott, Williams and Wilkins, 2005.
  • Introduction to Biomedical Imaging, Andrew Webb – John Wiley & Sons, Inc, 2003
References
    Planned learning activities and teaching methodsThe course is delivered to the students by means of lectures, conducted with the help of computer presentations, as well as demonstrations at the computer. Lecture notes and presentations are available through the web for students to use in combination with the textbooks.
    Assessment methods and criteria
    Assignments20%
    Test20%
    Final Exam60%
    Language of instructionEnglish
    Work placement(s)NO

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